Simulation Plus[SLP] SLP New Publications, 10th Feb 2025

안녕하세요? 퀀텀바이오솔루션즈입니다.


SLP 소프트웨어와 관련하여 새롭게 업데이트된 논문을 소개드립니다.


Physiologically Based Pharmacokinetic and Physiologically Based Biopharmaceutic models research in Latin America: A regional level bibliometric analysis, 2011-2023.

Ribeiro M, Cardoso JC, Martins JES, Pinto AF, Souto EMB, Severino P. (2025) Braz. J. Pharm. Sci. 61

Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, pbbm, virtual bioequivalence, vbe, drug product specifications, safe space, regulatory


Application of an Interdisciplinary Approach to Form Selection in Drug Development.

Reid DL, Faul MM, López-Mejías V, Agarwal P, Bergauer M, Blue LE, Chaves MK, Chung J, Cooke M, Farrell RP, Huckle JE, Kelly RC, Kiang YH, Li W, Ortiz A, Wu Q. (2025) Organic Process Research & Development Jan. 25

Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, pbbm, mechanistic absorption, acat, formulation assessment, biopharmaceutical risk assessment


Modeling and Simulation of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Healthy Adults Using the Quantitative Systems Toxicology Software Platform DILIsym.

Beaudoin JJ, Yang K, Howell BA, Kenz Z, Lakhani VV, Woodhead JL, Lai JCK, Gelotte CK, Sista S, Atillasoy E. (2025) CPT Pharmacometrics Syst Pharmacol. Feb 3

Keywords: gastroplus, dilisym, pbpk modeling, physiologically based pharmacokinetics, systems toxicology, hepatotoxicity, tinyTIM, formulation assessment


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