안녕하세요? 퀀텀바이오솔루션즈입니다.
SLP 소프트웨어와 관련하여 새롭게 업데이트된 논문을 소개드립니다.
Developing a Screening Strategy to Identify Hepatotoxicity and Drug Interaction Potential of Botanicals.
Roe AL, Krzykwa J, Calderón AI, Bascoul C, Gurley BJ, Koturbash I, Li AP, Liu Y, Mitchell CA, Oketch-Rabah H, Si L, van Breemen RB, Walker H, Ferguson SS. (2024) J Diet Suppl. Oct 25:1-31
Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, pbk, new approach methodologies, nam, risk assessment, chemicals
Machine learning driven bioequivalence risk assessment at an early stage of generic drug development.
Krajcar D, Velušček D, Grabnar I. (2024) Eur J Pharm Biopharm. Oct 25:114553
Keywords: gastroplus, admet predictor, machine learning, peff, logP, partition coefficient, vbe
Hydrogel for Sustained Delivery of Therapeutic Agents.
Musuc AM, Mititelu M, Chelu M. (2024) Gels. 10(11):717
Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, pbbm, biopharmaceutics, mechanistic absorption, formulation optimization, excipients
Evaluation of Drug–Drug Interactions Between Clarithromycin and Direct Oral Anticoagulants Using Physiologically Based Pharmacokinetic Models.
Yang Z, Qu Y, Sun Y, Pan J, Zhou T, Yu Y. Pharmaceutics (2024) 16(11):1449
Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, ddi, drug-drug interactions, p-gp, 3a4, enzymes, transporters
Physiologically-Based Pharmacokinetic Modeling of Trofinetide in Moderate Renal Impairment for Phase 1 Clinical Study Dose Selection with Model Validation.
Darwish M, Marbury TC, Nunez R, Youakim JM, An D, Darling I, Lukacova V, Bishop KM. (2024) Eur J Drug Metab Pharmacokinet. Nov 8
Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, dose optimization, special populations, disease modeling, renal impairment
주소 : 서울특별시 강남구 역삼로112 하나빌딩 301호
안녕하세요? 퀀텀바이오솔루션즈입니다.
SLP 소프트웨어와 관련하여 새롭게 업데이트된 논문을 소개드립니다.
Developing a Screening Strategy to Identify Hepatotoxicity and Drug Interaction Potential of Botanicals.
Roe AL, Krzykwa J, Calderón AI, Bascoul C, Gurley BJ, Koturbash I, Li AP, Liu Y, Mitchell CA, Oketch-Rabah H, Si L, van Breemen RB, Walker H, Ferguson SS. (2024) J Diet Suppl. Oct 25:1-31
Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, pbk, new approach methodologies, nam, risk assessment, chemicals
Machine learning driven bioequivalence risk assessment at an early stage of generic drug development.
Krajcar D, Velušček D, Grabnar I. (2024) Eur J Pharm Biopharm. Oct 25:114553
Keywords: gastroplus, admet predictor, machine learning, peff, logP, partition coefficient, vbe
Hydrogel for Sustained Delivery of Therapeutic Agents.
Musuc AM, Mititelu M, Chelu M. (2024) Gels. 10(11):717
Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, pbbm, biopharmaceutics, mechanistic absorption, formulation optimization, excipients
Evaluation of Drug–Drug Interactions Between Clarithromycin and Direct Oral Anticoagulants Using Physiologically Based Pharmacokinetic Models.
Yang Z, Qu Y, Sun Y, Pan J, Zhou T, Yu Y. Pharmaceutics (2024) 16(11):1449
Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, ddi, drug-drug interactions, p-gp, 3a4, enzymes, transporters
Physiologically-Based Pharmacokinetic Modeling of Trofinetide in Moderate Renal Impairment for Phase 1 Clinical Study Dose Selection with Model Validation.
Darwish M, Marbury TC, Nunez R, Youakim JM, An D, Darling I, Lukacova V, Bishop KM. (2024) Eur J Drug Metab Pharmacokinet. Nov 8
Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, dose optimization, special populations, disease modeling, renal impairment