Simulations Plus[SLP] SLP New Publications, 24th Aug 2024

안녕하세요? 퀀텀바이오솔루션즈입니다. 


SLP 소프트웨어와 관련하여 새롭게 업데이트된 논문을 소개드립니다.


Novel omeprazole delayed release orally disintegrating tablets for enhanced patient compliance: a case of model informed formulation development.

Boddu R, Kollipara S, Kambam V, Khan SM, Behera S, Murty NN, Baheti N, Choudhury AA, Ahmed T. (2024) Xenobiotica. Aug 21:1-13

Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, pbbm, biopharmaceutics, midd, bioequivalence, vbe


Design and Evaluation of 3-Phenyloxetane Derivative Agonists of the Glucagon-Like Peptide-1 Receptor.

Zhang Z, Pan H, Guo L, Cai C, Chen T, Zhang Z, Yang X, Zheng H, Jiang C, Wang Z, Yang Y, Wang Z, Zhang X, Zhang Y, Liu D. (2024) J Med Chem. Aug 14

Keywords: gastroplus, admet predictor, pbpk modeling, physiologically based pharmacokinetics, aidd, drug design, lead selection, cadd, high throughput pk


A Physiologically Based Pharmacokinetic Model of Voriconazole in Human CNS —— Integrating Time-Dependent Inhibition of CYP3A4, Genetic Polymorphisms of CYP2C19 and Possible Transporter Mechanisms.

Dong L, Zhuang X, Yang T, Yan K, Cai Y. (2024) Int J Antimicrob Agents. Aug 19:107310

Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, ivive, translational science, preclinical development, neuroscience, brain penetration, drug-drug interaction, ddi, population simulation, transporters


A Semi-Mechanistic Physiologically Based Biopharmaceutics Model to Describe Complex and Saturable Absorption of Metformin: Justification of Dissolution Specifications for Extended Release Formulation.

Bhattiprolu AK, Kollipara S, Boddu R, Arumugam A, Khan SM, Ahmed T. (2024) AAPS PharmSciTech. Aug 21;25(7):193

Keywords: gastroplus, pbpk modeling, physiologically based pharmacokinetics, pbbm, biopharmaceutics, mechanistic absorption, safe space, bioequivalence, vbe

주소 : 서울특별시 강남구 역삼로112 하나빌딩 301호
대표번호 : 02-568-0646
상호명 : 퀀텀바이오솔루션즈
제품문의 : quantumbiosolutions@gmail.com
사업자등록번호 : 209-81-50993
기술지원 : support@qbio.co.kr